Enhancing Enzyme-like Activities of Prussian Blue Analog Nanocages by Molybdenum Doping: Toward Cytoprotecting and Online Optical Hydrogen Sulfide Monitoring

References

ref title DOI material type comment
3643 456 Enhancing Enzyme-like Activities of Prussian Blue Analog Nanocages by Molybdenum Doping: Toward Cytoprotecting and Online Optical Hydrogen Sulfide Monitoring https://doi.org/10.1021/acs.analchem.0c01028 Composite Molybdenum-polysulfide-deposited nickel–iron bimetal Prussian-blue-analog-based hollow nanocages (Nanocages)

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7690 456 PBAs 60 nm TEM The size of the PBAs was accurately controlled to be ∼60 nm with smooth surfaces through a 40 °C water-bath-assisted synthesis (Figure S1A,B, Supporting Information). The elements Ni and Fe existed in the PBA in the energy-dispersive X-ray spectroscopy (EDS) spectrum (Figure S1C) and in the elemental mapping images (Figure S1D), which indicated that the bimetal nanocubes were well synthesized. From the TEM images of the Nanocages (Figure 1A), a cubic morphology with an average size of 60 nm was retained, but the cube became hollow and the surfaces became much rougher. 60.11

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
6308 456 Nanocages OXD Dopamine 9.82 μM 3.67 -8 M/s 456

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5376 456 Nanocages The peroxidase- and catalase-mimicking activities were applied to eliminate reactive oxygen species in cells
5375 456 Nanocages the laccase-like activity of Nanocages was integrated with an online sensing platform for in vivo and continuous optical hydrogen sulfide monitoring in the brains of living rats hydrogen sulfide E-chem 0.1-15 μM 33 nM
5374 456 Nanocages the laccase-like activity of Nanocages was integrated with an online sensing platform for in vivo and continuous optical hydrogen sulfide monitoring in the brains of living rats hydrogen sulfide E-chem 0.1-15 μM 33 nM After testing the excellent capabilities of the OODP toward H2S monitoring, the animal model was carried out to test the ability of the constructed method.