Ultrasound-Enhanced Generation of Reactive Oxygen Species for MRI-Guided Tumor Therapy by the Fe@Fe3O4-Based Peroxidase-Mimicking Nanozyme

References

ref title DOI material type comment
3686 499 Ultrasound-Enhanced Generation of Reactive Oxygen Species for MRI-Guided Tumor Therapy by the Fe@Fe3O4-Based Peroxidase-Mimicking Nanozyme https://doi.org/10.1021/acsabm.9b01006 Composite Fe@Fe3O4@heparin

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7728 499 Fe3O4@heparin 0.044 U/mg
7727 499 Fe@Fe3O4@heparin 13.9 1.7 nm TEM water-soluble Fe@Fe3O4 NPs were modified with heparin through the ligand exchange method to form Fe@Fe3O4@heparin NPs (MNPs). 0 U/mg
7726 499 Fe3O4@heparin 0 U/mg
7725 499 Fe@Fe3O4@heparin 13.9 1.7 nm TEM water-soluble Fe@Fe3O4 NPs were modified with heparin through the ligand exchange method to form Fe@Fe3O4@heparin NPs (MNPs). 0.456 U/mg

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
6357 499 Fe3O4@heparin POD TMB 5.2 48.83 mM 2.21 -8 M/s 499 499
6356 499 Fe3O4@heparin POD H2O2 5.2 0.55 mM 35.66 -8 M/s 499
6355 499 Fe@Fe3O4@heparin POD TMB 5.2 0.12 mM 3.82 -8 M/s 499 还用US(超声)照射之后再测了活性

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment