ref | title | DOI | material type | comment | |
---|---|---|---|---|---|
3896 | 710 | Nanozyme-Augmented Tumor Catalytic Therapy by Self-Supplied H2O2 Generation | https://doi.org/10.1021/acsabm.0c00056 | Composite | Herein, we fabricated a nanozyme platform (Fe@Fe3O4@Cu2-xS, named as MNPs) possessing peroxidase enzyme-like activity, and then introduced β-Lapachone (La) to assemble an effective nanozyme (LaMNPs) to boost the production of reactive oxygen species and upregulate the level of H2O2 by the released La in an acidic tumor microenvironment |
ref | material | size | size err | size unit | size type | size comment | BET | b nanozyme | b 10n | b unit | specific act | sa 10n | sa unit | comment | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7922 | 710 | LaMNPs-PEG | 71 | nm | DLS | The HD and potential of LaMNPs-PEG were about ~71 nm and ~-27.3 mV by dynamic light scattering (DLS) |
ref | material | enzyme type | substrate | pH | T | km | km err | km 10n | km unit | vmax | vmax err | vmax 10n | vmax unit | kcat | kcat err | kcat 10n | kcat unit | kcat/km | kcat/km 10n | kcat/km unit | comment | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
6592 | 710 | MNPs-PEG | POD | TMB | 0.18 | mM | 54 | -8 | M/s | 710 | ||||||||||||
6591 | 710 | MNPs-PEG | POD | H2O2 | 0.17 | mM | 42 | -8 | M/s | 710 |
ref | material | application | target | method | linear range | linear ran unit | LOD | lod unit | recovery | comment | |
---|---|---|---|---|---|---|---|---|---|---|---|
5635 | 710 | LaMNPs | inhibition of the tumor growth |