A metal-free nanozyme-activated prodrug strategy for targeted tumor catalytic therapy

References

ref title DOI material type comment
3313 82 A metal-free nanozyme-activated prodrug strategy for targeted tumor catalytic therapy https://doi.org/10.1016/j.nantod.2020.100935 Carbon phosphorous and nitrogen dual-doped porous hollow carbon sphere

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7386 82 PNCNzyme 100 10 nm TEM uniform size of approximately 100 ± 10 nm in diameterwith hollow and porous structure

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
5978 82 PNCNzyme POD H2O2 154.8 mM 54.22 -8 M/s 82 82
5977 82 PNCNzyme POD TMB 0.07915 mM 22.82 -8 M/s 82 82

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
4995 82 PNCNzyme Activating IAA to produce abundant ROS and triggering tumor cell apo-ptosis