Construction and characterization of magnetic cascade metal-organic framework/enzyme hybrid nanoreactors with enhanced effect on killing cancer cells

References

ref title DOI material type comment
4025 839 Construction and characterization of magnetic cascade metal-organic framework/enzyme hybrid nanoreactors with enhanced effect on killing cancer cells https://doi.org/10.1016/j.colsurfa.2020.124990 Composite magnetic metal-organic framework (zeolitic imidazolate framework 8, ZIF-8) nanoparticles (NPs) with ferrimagnetic structures inside loaded with GOx(Fe@ZIF-8@GOx NRs)

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
8037 839 Fe@ZIF-8@GOx NRs 635 180 nm DLS The obtained Fe@ZIF-8@GOx NRs showed an average size of 635 ± 180 nm in DMEM/10%FBS, which is larger than that measured from SEM images.

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
6738 839 Fe@ZIF-8@GOx NRs cascade reaction Glucose 11.04 mM 3.35 -8 M/s 839

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5767 839 Fe@ZIF-8@GOx NRs kill cancer cells