Carbon nanocage-based nanozyme as an endogenous H 2 O 2-activated oxygenerator for real-time bimodal imaging and enhanced phototherapy of esophageal cancer

References

ref title DOI material type comment
4103 917 Carbon nanocage-based nanozyme as an endogenous H 2 O 2-activated oxygenerator for real-time bimodal imaging and enhanced phototherapy of esophageal cancer https://doi.org/10.1039/D0NR05945E Composite

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
8109 917 BSA-MnO2/IR820@OCNC 100 nm TEM Transmission electron microscopy (TEM) was used to confirm the structures of the various nanomaterials. The CNCs appeared as hollow nanoscale structures, which explains their high loading capacity (Fig. 1B). Furthermore, significant particle aggregation was observed in the TEM image; this was attributed to their poor hydrophilicity. BSA-MnO2 nanoparticles were generally spherical and well dispersed, with a uniform particle size (Fig. 1C). After attaching abundant carboxyl groups to the surface of the CNCs, loading with IR820, and decorating with BSA-MnO2, the BMIOC nanosystem was successfully obtained (Fig. 1D and E).

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
6821 917 BSA-MnO2/IR820@OCNC CAT H2O2 917

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5830 917 BSA-MnO2/IR820@OCNC antitumor H2O2