| 4994 |
78 |
AuNP-ICA platform |
Detection of Escherichia coli O157:H7 in Milk |
E. coli |
Color |
5-2.5*10^5 |
CFU/mL |
12.5 |
CFU/mL |
90.94 |
|
| 5001 |
92 |
Rhodium |
Anti-Inflammation and Antitumor Theranostics of Colon Diseases |
RONS |
Fluor |
|
|
|
|
|
|
| 5004 |
96 |
AuNCs |
detaction of tetracycline antibiotics |
tetracycline antibiotics |
Color |
1-16 |
μM |
46 |
nM |
|
|
| 5044 |
144 |
Au21Pd79 |
glucose detection |
glucose |
Color |
5-400 |
μM |
0.85 |
μM |
|
|
| 5056 |
155 |
Au NCs-ICG |
Cancer therapy |
|
|
|
|
|
|
|
|
| 5080 |
171 |
HS-PtNPs |
These obvious advantages prompted us to explore the practical use of HS-PtNPs. The pyridine ring of isoniazid has strong reductive hydrazyl substitution, which can compete with TMB for the catalytic site of HS-PtNPs (Scheme 1). The introduction of isoniazid in HS-PtNPs-catalyzed oxidation process of TMB results in a lower efficiency and colorless reaction in TMB oxidation. |
isoniazid |
Color |
2.5-250 |
μM |
1.7 |
μM |
95%-103% |
|
| 5119 |
206 |
Au-nanozyme |
selective and sensitive detection of mercury(II) |
Hg2+ |
Color |
0.14–7.35 |
mg L−1 |
20 |
µg L−1 |
|
The method is appropriate for the analysis of Hg2+ in water samples. |
| 5120 |
206 |
Au-nanozyme |
selective and sensitive detection of mercury(II) |
Hg2+ |
Color |
0.14–7.35 |
mg L−1 |
20 |
µg L−1 |
|
|
| 5139 |
226 |
Pt NPs |
sensitive and rapid detection of carcinoembryonic antigen (CEA), pressure-based point-of-care (POC) testing strategy |
carcinoembryonic antigen (CEA) |
Unsure |
0.2-60 |
ng/mL |
0.13 |
ng/mL |
|
|
| 5150 |
259 |
Pd4 Pd6 |
ROS scavenging effects of PdNPs in a cellular model of oxidative stress-related disease |
|
|
|
|
|
|
|
|
| 5152 |
260 |
GSH@PtNPs |
Cu2+ detection |
Cu2+ |
Color |
25-300 |
nM |
6.8 |
nM |
|
|
| 5151 |
260 |
GSH@PtNPs |
Cu2+ detection |
Cu2+ |
Color |
50-800 |
nM |
7 |
nM |
|
Cu2+ ions in real human serum samples were detected |
| 5164 |
273 |
PtGs |
Synergistic oxygen-inductive starvation/electrodynamic tumor therapy |
|
|
|
|
|
|
|
|
| 5172 |
278 |
AuNP |
study under non-equilibrium conditions |
|
|
|
|
|
|
|
|
| 5182 |
292 |
RuTeNRs |
cancer treatment |
|
|
|
|
|
|
|
|
| 5215 |
324 |
Cu NCs |
detection of AA |
DFQ |
Fluor |
0.5-30 |
μM |
0.144 |
μM |
|
|
| 5217 |
324 |
Cu NCs |
detection of H2O2 |
H2O2 |
Color |
0.01-1 |
mM |
5.6 |
μM |
|
|
| 5216 |
324 |
Cu NCs |
detection of GSH |
GSH |
Color |
1-150 |
μM |
0.89 |
μM |
|
|
| 5237 |
336 |
OEG-AuNPs |
Detection of Hg2+ |
Hg2+ in Tap water |
|
10-40 |
ppb |
2 |
ppb |
|
|
| 5238 |
336 |
OEG-AuNPs |
Detection of Hg2+ |
Hg2+ in dH2O |
Color |
10-60 |
ppb |
0.9 |
ppb |
|
|
| 5234 |
336 |
OEG-AuNPs |
Detection of Hg2+ |
Hg2+ in saline solution |
|
20-120 |
ppb |
13 |
ppb |
|
|
| 5235 |
336 |
OEG-AuNPs |
Detection of Hg2+ |
Hg2+ in seawater |
|
20-100 |
ppb |
10 |
ppb |
|
|
| 5236 |
336 |
OEG-AuNPs |
Detection of Hg2+ |
Hg2+ in bottled water |
|
10-40 |
ppb |
2 |
ppb |
|
|
| 5241 |
338 |
Pt@Au |
Detection of Zika virus |
Zika virus |
Color |
1-1000 |
pg/mL |
|
|
|
|
| 5243 |
339 |
AuNCs@CTAB |
human chorionic gonadotropin detection |
human chorionic gonadotropin |
Color |
|
mIU/mL |
31.2 |
mIU/mL |
|
|
| 5244 |
339 |
AuNSs@CTAB |
human chorionic gonadotropin detection |
human chorionic gonadotropin |
Color |
7.8-10000 |
mIU/mL |
7.8 |
mIU/mL |
|
|
| 5242 |
339 |
AuNRs@CTAB |
human chorionic gonadotropin detection |
human chorionic gonadotropin |
Color |
|
mIU/mL |
15.6 |
mIU/mL |
|
|
| 5245 |
340 |
AuNPs |
Escherichia coli detection |
Escherichia coli |
Color |
10-10E9 |
CFU/mL |
10 |
CFU/mL |
|
|
| 5256 |
353 |
Au@Pt-nanoparticles |
on-site and quantitative detection of Escherichia coli O157:H7 |
|
|
|
|
|
|
|
|
| 5259 |
357 |
PtNFs |
the quantitative detection of DHEA in human urine |
DHEA |
Color |
2.1- 118.1 |
ng mL−1 |
1.3 |
ng mL−1 |
|
The IC50 value is 15.7 ng mL−1, LOD is 1.3 ng mL−1, and the linear range is 2.1 ~ 118.1 ng mL−1, |
| 5260 |
357 |
PtNFs |
the quantitative detection of DHEA in human urine |
DHEA |
Color |
2.1- 118.1 |
ng mL−1 |
1.3 |
ng mL−1 |
|
|
| 5264 |
362 |
Aptamer-gold nanozyme |
to develop an Aptamer-nanozyme lateral flow assay (ALFA) |
CA125 in human serum |
CL |
7.5-200 |
U/mL |
5.21 |
U/mL |
|
|
| 5271 |
366 |
Pd−Ir core-shell nanoparticles |
This work not only demonstrates the size effect, but also provides an effective strategy to enhance the performance of nanozymes in certain applications. |
|
|
10- 2000 |
pg/mL |
8.2, 4.6, and 3.7 |
pg/mL |
|
|
| 5272 |
366 |
Pd−Ir core-shell nanoparticles |
This work not only demonstrates the size effect, but also provides an effective strategy to enhance the performance of nanozymes in certain applications. |
|
|
10- 2000 |
pg/mL |
8.2, 4.6, and 3.7 |
pg/mL |
|
the limit of detection (LOD, which was defined by the 3SD method33) for the ELISAs were lowered from 9.3, to 8.2, 4.6, and 3.7 pg/mL when the size of Pd−Ir NPs was reduced from 13.0 to 9.8, 5.9, and 3.3 nm, respectively. |
| 5292 |
383 |
AuNPs@Ag |
detect the viral HEV containing in fecal samples collected from HEV-infected monkey |
HEV-LPs |
Color |
8.75 × 10−8– 10−11 |
g mL−1 |
4.3 × 10−12 |
g mL−1 |
|
|
| 5294 |
386 |
PEI-AgNCs |
With the above understanding, the PEI-AgNC-catalyzed TMB + Cr6+ chromogenic reaction is able to be employed to detect toxic Cr6+ photometrically. |
Cr3+ |
Color |
5~100 |
μM |
3.7 |
μM |
|
|
| 5300 |
390 |
Nanozymes with hard coronas (Corona-NZ) |
We observed that the structure of the AuNP ligands dictates the formation of protein coronas and selectively controls catalytic activity of nanozymes. A hard “irreversible” corona (without TEG) deactivated nanozymes through aggregation and steric blocking, while a soft “reversible” corona (with TEG) partially reduced the catalytic activity. The catalytic activity of both soft and hard nanozymes was restored after proteolytic degradation of the protein corona through endogenous proteases present in the endosome and lysosome. Hence, a selective intracellular activation system (without TEG) and an always-on system (with TEG) are obtained by engineering the monolayer of ligands on nanoparticles. This study provides a direct and versatile approach for specific activation of bioorthogonal catalysts through tuning the formation of the protein corona on nanozymes. This approach has the potential to reduce the off-target effect and extend on-demand generation of imaging agents and localized therapeutics. The generality of this system is suitable for in vivo applications, which are currently under investigations in our group. |
|
|
|
|
|
|
|
|
| 5313 |
407 |
Au NPs |
|
Hg2+ |
surface plasmon resonance |
1-2000 |
pM |
0.46 |
pM |
|
|
| 5346 |
436 |
MPBs |
detection of uric acid in whole blood |
UA |
Color |
1.5-8.5 |
mg/dL |
|
|
|
The mHealth LFP could achieve a wide detection range of 1.5-8.5 mg/dL UA. |
| 5345 |
436 |
MPBs |
detection of uric acid in whole blood |
UA |
Color |
1.5-8.5 |
mg/dL |
|
|
|
|
| 5348 |
437 |
Au NP |
protein detection |
|
|
|
|
|
|
|
|
| 5347 |
437 |
Au NP |
protein detection |
|
|
|
|
|
|
|
A colorimetric sensor array for protein detection is developed. |
| 5371 |
453 |
Pt |
Colorimetric Determination of Total Antioxidant Level in Saliva |
|
|
|
|
|
|
|
|
| 5372 |
453 |
Pt |
Colorimetric Determination of Total Antioxidant Level in Saliva |
|
|
|
|
|
|
|
TAC levels of saliva samples collected from 83 healthy volunteers, aged between 20 and 50 years, measured by the nanozyme-based assay. |
| 5373 |
454 |
Anti-PSA-Ab Coated Au NPs |
Sensitive Colorimetric Detection of Prostate Specific Antigen |
BSA |
Color |
0.25-2500 |
ng/mL |
0.23 |
ng/mL |
|
|
| 5396 |
466 |
4-AHA@AuNPs nanoparticles |
selective determination of mercury and iron in ground water |
Fe3+ |
Color |
5–50 |
ppb |
4.0 |
ppb |
|
|
| 5395 |
466 |
4-AHA@AuNPs nanoparticles |
selective determination of mercury and iron in ground water |
Hg2+ |
Color |
5-200 |
ppb |
2.5 |
ppb |
|
|
| 5453 |
509 |
AuNPs@C.CNF |
Detection of glucose |
glucose |
Color |
1–60 |
μM |
0.67 |
μM |
|
|
| 5452 |
509 |
AuNPs@C.CNF |
Detection of H2O2 |
H2O2 |
Color |
0.5–30 |
μM |
0.30 |
μM |
|
|
| 5457 |
513 |
FA-AgNPs |
for rheumatoid arthritis therapy |
|
|
|
|
|
|
|
|
| 5458 |
515 |
aptamers@BSA-AuNCs |
for colorimetric detection of Salmonella typhimurium |
Salmonella typhimurium |
Color |
101-106 |
cfu/mL |
1 |
cfu/mL |
92.4% - 110% |
|
| 5460 |
518 |
Hep-Pt NCs |
Colorimetric tests of H2O2 and glucose |
glucose |
Color |
0.1 ∼ 2.0 |
mM |
33 |
μM |
98%-104.0% |
|
| 5487 |
543 |
Au@SiO2-NH2 |
Gold nanorod-based nanoplatform catalyzes constant NO generation and protects from cardiovascular injury |
|
|
|
|
|
|
|
|
| 5491 |
549 |
β-CD@AuNPs |
sense PPase activity at neutral pH |
|
colorimetric and photothermal |
|
|
|
|
|
|
| 5501 |
561 |
urchin-like Pt nanozymes |
monitoring of glycated albumin |
glycated albumin |
Color |
10-5000 |
ug/mL |
9.2 |
ug/mL |
106-107 |
|
| 5507 |
569 |
Au NPs |
DNA release |
|
|
|
|
|
|
|
|
| 5586 |
658 |
AuNPs |
detection cysteine |
|
Color |
0.5-20 |
μM |
0.5 |
μM |
|
|
| 5587 |
658 |
AuNPs |
detection cysteine in biological fluids |
|
Color |
0.5-50 |
μM |
0.5 |
μM |
|
To this end, we tested human urine samples for different concentrations of cysteine using the system established in this paper. |
| 5596 |
666 |
AuNCs-SF |
detection of H2O2 |
H2O2 |
Fluor |
0.1-100 |
mM |
0.072 |
mM |
95.12-99.76% |
|
| 5598 |
668 |
D-Trp-OMe@AuNCs |
detection of trtracycline |
TMB |
Color |
1.5-30.0 |
μM |
0.20 |
μM |
99.0-105.0% |
|
| 5601 |
671 |
IrNPs |
antibacteria |
|
|
|
|
|
|
|
|
| 5623 |
695 |
Pt |
detect ascorbic acid in triplicate |
Ascorbic acid (AA) |
Color |
1-20 |
μM |
|
|
|
The limits of detection were 131 ± 15, 144 ± 14, and 152 ± 9 nM, with little difference. |
| 5632 |
707 |
AuNPs |
detection of Opisthorchis viverrini antigen (OvAg) in urine samples |
Opisthorchis viverrini antigen (OvAg) |
Color |
|
|
23.4 |
ng mL-1 |
|
|
| 5649 |
727 |
Ir NPs |
detection of glutathione |
GSH |
Color |
0.2-100 |
μM |
|
|
|
|
| 5650 |
727 |
Ir NPs |
detection of glucose |
glucose |
Color |
0.01-2 |
mM |
5.8 |
μM |
93.3–104% |
|
| 5683 |
754 |
Pt nanocrystals |
The Pt nanocrystals also display laccase mimicking activity, which can be harnessed for colorimetric assay of epinephrine with high sensitivity. |
epinephrine |
Color |
4.55−172.98 |
μM |
0.66 |
μM |
98-103 |
|
| 5713 |
788 |
AuNPTs |
antibacterial therapy |
|
|
|
|
|
|
|
|
| 5720 |
794 |
PB |
skin wound healing |
|
|
|
|
|
|
|
|
| 5730 |
803 |
PtNP |
sensitive electrochemical immunosensor for thyroid-stimulating hormone detection |
TSH |
E-chem |
0.3-1000000 |
pg |
0.3 |
pg/mL |
|
|
| 5732 |
807 |
AuNPs |
determination of glucose |
glucose |
Color |
5-125 |
μM |
3.4 |
μM |
99.0-101.6% |
The IFE-based assay system was utilized for determining the levels of glucose in urine samples of a diabetic patients. |
| 5733 |
807 |
AuNPs |
detection of hydrogen peroxide |
H2O2 |
Color |
5-135 |
μM |
3.6 |
μM |
|
|
| 5735 |
810 |
GOx@Au@MagSiO2 |
One-pot, direct glucose detection |
glucose |
Color |
0.44–17.78 |
mM |
0.66 |
mM |
|
The calibration plots obtained with the blood volume fractions of 0.20 and 0.46 mL/mL can be eventually used for direct determination of blood glucose concentration in the range of 0.5–7.0 mg/mL blood (2.8–38.9 mM). |
| 5737 |
812 |
Cu NCs |
The reactivity toward peroxide is utilized in specific and sensitive sensing of glucose |
glucose |
Fluor |
0-1 |
mM |
7.56 |
μM |
99-99.6% |
|
| 5736 |
812 |
Cu NCs |
a ratiometric H2O2 sensor |
H2O2 |
Fluor |
0-1 |
mM |
4.66 |
μM |
|
|
| 5747 |
821 |
[Pyr]Ac- Ni0 |
detection of H2O2 |
H2O2 |
Color |
400-4000 |
μM |
120 |
μM |
|
|
| 5768 |
840 |
AuNPs |
highly sensitive and specific identification of Aflatoxin B1 |
Aflatoxin B1 |
Color |
5-5120 |
nM |
1.88 |
nM |
91.5–117.6% |
|
| 5807 |
881 |
FePOs |
anti-tumor protocol |
|
|
|
|
|
|
|
|
| 5808 |
882 |
Magnetite |
detect H2O2 |
H2O2 |
|
2.4 × 104 μAM−1 and 1.8 × 10−5 M |
|
|
|
|
|
| 5809 |
883 |
PVP-PtNC |
this “off-to-on” pathway makes the nanozyme-based colorimetric signal proportional to AMD concentrations, thereby circumventing the inherent drawbacks of limited signaling abilities and sensitivities with conventional signal-off immunoassay-based small molecule detection systems. AMD |
amantadine (AMD) |
|
|
|
|
|
|
|
| 5815 |
889 |
Ptn-JP NCs |
for glucose detection |
glucose |
Color |
0.01 -1 |
mM |
5.47 |
μM |
|
|
| 5816 |
895 |
BSA-MgNPs |
for Scavenging Hydrogen Peroxide from Human Hepatic Cells |
|
|
|
|
|
|
|
|
| 5817 |
896 |
Ptn-PEI NPs |
Glucose Detection |
glucose |
Color |
0.01-5 |
mM |
4.2 |
μM |
|
|
| 5821 |
903 |
AuNPs |
Analysis of gas Samples |
CO |
SERS |
|
|
|
|
|
|
| 5824 |
908 |
Au(111) |
chiral selective oxidation |
glucose |
|
|
|
|
|
|
|
| 5862 |
958 |
Silver citrate |
Determination of phenolic pollutants and adrenaline |
Phenolic pollutants |
|
2.35 714 |
µ M |
1.33 |
µ M |
|
|
| 5864 |
961 |
Au NC's |
Detection of antioxidants |
AA,GSH,Cys |
Fluor |
0.005 -10 |
μ M |
0.04 |
μ M |
|
|
| 5865 |
962 |
Pt |
Immunochromatographic test strip for detecting aflatoxin B1 (AFB1) |
|
Color |
0.05 – 10 |
ng /mL |
0.03 |
ng /mL |
|
|
| 5869 |
966 |
Au |
Detection of uric acid in human serum and urine |
Uric acid |
Color |
0.1 to 30 |
μ M |
0.04 |
μ M |
|
|
| 5870 |
967 |
Au |
Detection of arsenite |
Arsinite |
Color |
0.01 – 11.67 |
mg/L |
0.008 |
mg/L |
|
|
| 5881 |
978 |
Au NPs |
Digital glucose detction |
|
|
0-10 |
mg/mL |
|
|
|
|
| 5894 |
988 |
Cy-AuNCs |
detection of glutathione reductase (GR) |
GR |
Color |
0-0.2 |
U/mL |
0.003 |
U/mL |
|
|
| 5892 |
988 |
Cy-AuNCs |
detection of glutathione (GSH) |
GSH |
Color |
0-0.4 |
mM |
0.01 |
mM |
|
|
| 5893 |
988 |
Cy-AuNCs |
detection of glutathione disulfide |
glutathione disulfide |
Color |
0-2.5 |
mM |
0.03 |
mM |
|
|
| 5913 |
1005 |
Pt-PIL-MWCNTs |
Detection of Glucose |
Glucose |
Color |
160-900 |
μM |
50 |
μM |
|
|
| 5914 |
1005 |
Pt-PIL-MWCNTs |
Detection of H2H2 |
H2O2 |
Color |
10-1000 |
μM |
5.5 |
μM |
|
|
| 5924 |
1015 |
AA-PtNPs |
Detection of Ag+ and AgNPs |
Ag+ |
Unsure |
5-250 |
nM |
2.0 |
μM |
|
|
| 5925 |
1015 |
AA-PtNPs |
Detection of Ag+ and AgNPs |
AgNPs |
|
10-300 |
pM |
3.8 |
μM |
|
|
| 5965 |
1057 |
Au NBPs |
visual detection of ochratoxin A |
OTA |
Color |
1-5000 |
ng/L |
0.47 |
ng/L |
|
|
| 5989 |
1078 |
Au NPs |
Colorimetric detection of chiral monosaccharide |
chiral monosaccharide |
Color |
|
|
|
|
|
|
| 5990 |
1079 |
Copper Nanozyme |
degradation of methyl orange pollutants |
methyl orange |
|
|
|
|
|
|
|
| 6007 |
1098 |
AUNCs |
prodrug activation |
nitrobenzene |
|
|
|
|
|
|
|
| 6018 |
1110 |
AgPd0.38 |
antibacterial |
|
|
|
|
|
|
|
|
| 6025 |
1118 |
Cu NanoZyme |
detection of glucose in human urine |
glucose |
Color |
0.5-15 |
mM |
0.45 |
mM |
|
|
| 6031 |
1127 |
1-Me-D-Trp@AuNCs |
Norfloxacin detection |
Norfloxacin detection |
Color |
1.25~8.0 |
μM |
0.2 |
μM |
|
|
| 6045 |
1148 |
Pd NCs |
quantitatively monitoring heparin in aqueous solution and biological fluid |
heparin |
Color |
0.5–25 |
µg mL−1 |
1.1 |
ng mL−1 |
|
|
| 6059 |
1165 |
CuNFs |
immunoassay demonstrates high sensitivity for IV/A |
influenza virus (IV)/A |
|
10–10*6 |
fg mL−1 |
32.37 |
fg mL−1 |
|
a limit of detection (LOD) as low as 32.37 fg mL−1 and 54.97 fg mL−1 in buffer and serum, respectively. For practical needs, a clinically isolated IV/A/H3N2 and spike protein of SARS-CoV-2 were detected with the LODs of 17 pfu mL−1 and 143 fg mL−1, respectively. |
| 6093 |
1209 |
Cu/CeS |
Cu/CeS-based sensor for H2O2 determination showed high sensitivity |
H2O2 |
|
1.5–20,000 |
μM |
0.42+0.006 |
|
|
|
| 6147 |
1287 |
GNE-based Au NPs |
Glucose Biosensor |
glucose |
Color |
0.05-10 |
mM |
|
|
|
|
| 6148 |
1287 |
GNE-based Au NPs |
H2O2 detection |
H2O2 |
CL |
|
|
|
|
|
|
| 6152 |
1297 |
Rh NPs |
Immunosensor for Ferritin (RhNPs-lateral flow immunoassay with enhancement ) |
Ferritin |
Color |
0.01-5 |
ng/mL |
0.3 |
ng/mL |
|
|
| 6153 |
1297 |
Rh NPs |
Immunosensor for Ferritin (RhNPs-lateral flow immunoassay without enhancement ) |
Ferritin |
Color |
0.1-10 |
ng/mL |
0.4 |
ng/mL |
|
|
| 6161 |
1308 |
Cu NPs |
Prodrug conversion reactions. |
Salicylic acid acyl-β-d-glucuronide |
Unsure |
|
|
|
|
|
|
| 6171 |
1323 |
|
Detection of pro-gastrin-releasing peptide |
pro-gastrin-releasing peptide |
E-chem |
0.001-10 |
ng/mL |
0.86 |
ng/mL |
|
|
| 6175 |
1326 |
SBA-AmPA/Au |
reduction of 4-nitrophenol |
|
|
|
|
|
|
|
|
| 6194 |
1344 |
AgNCs |
as new alternative therapeutics against MDR P. aeruginosa |
|
|
|
|
|
|
|
|
| 6205 |
1354 |
Au NPs |
Nanozymatic Label-free Detection of Acid Phosphatase. |
Acid phosphatase (ACP) |
Color |
0.01-50 |
mU/mL |
0.03 |
mU/mL |
|
|
| 6239 |
1385 |
Co2+ |
Determination of Co2+ |
Co2+ |
Color |
10-300 |
μM |
0.4 |
μM |
|
|
| 6247 |
1397 |
citrate-Os NPs |
detection of glucose |
glucose |
Color |
5-200 |
μM |
0.4 |
μM |
91.5-103.1 |
|
| 6248 |
1397 |
citrate-Os NPs |
detection of pyruvic acid |
pyruvic acid |
Color |
10-130 |
μM |
0.4 |
μM |
91.3-101.0 |
|
| 6267 |
1417 |
Au@SiO2@Fe3O4@SiO2 microspheres |
GSH detection |
GSH |
Color |
37.5-325 and 325-3300 |
μM |
|
|
|
The GSH concentration was also determined in human serum |
| 6284 |
1435 |
PdNCs |
H2O2 detection |
H2O2 |
Color |
5-50 |
μM |
0.0625 |
µM |
|
|
| 6285 |
1436 |
Ag@PANI |
To detect saccharides |
|
SERS |
|
|
100 |
nM |
|
|