Nanozyme Database

Materials

Enzyme-like Activity

	ref	title	DOI	material type	comment
3242	11	Heme Cofactor-Resembling Fe–N Single Site Embedded Graphene as Nanozymes to Selectively Detect H2O2 with High Sensitivity	https://doi.org/10.1002/adfm.201905410	Others	Fe–N4 single site embedded graphene (Fe–N-rGO)
3243	12	Highly bioactive zeolitic imidazolate framework-8–capped nanotherapeutics for efficient reversal of reperfusion-induced injury in ischemic stroke	https://doi.org/10.1126/sciadv.aay9751	MOF	zeolitic imidazolate framework-8–capped ceria nanoparticles (CeO2@ZIF-8 NPs)
3244	13	Inorganic nanoparticles with enzyme-mimetic activities for biomedical applications	https://doi.org/10.1016/j.ccr.2019.213092		review
3245	14	Cerium Oxide Nanoparticles Improve Outcome after In Vitro and In Vivo Mild Traumatic Brain Injury	https://doi.org/10.1089/neu.2016.4644	Composite
3246	15	Improving cancer therapy through the nanomaterials-assisted alleviation of hypoxia	https://doi.org/10.1016/j.biomaterials.2019.119577		review
3247	16	Ultrafine Titanium Monoxide (TiO1+x) Nanorods for Enhanced Sonodynamic Therapy	https://doi.org/10.1021/jacs.9b10228	Metal oxide
3248	17	Biodegradation-Mediated Enzymatic Activity-Tunable Molybdenum Oxide Nanourchins for Tumor-Specific Cascade Catalytic Therapy	https://doi.org/10.1021/jacs.9b13586	Metal oxide	MoO3–x Nus
3249	18	Ultrasensitive aptamer-based protein assays based on one-dimensional core-shell nanozymes	https://doi.org/10.1016/j.bios.2019.111881	Metal oxide	Fe3O4@C nanowire
3250	19	Cu-nanoflower decorated gold nanoparticles-graphene oxide nanofiber as electrochemical biosensor for glucose detection	https://doi.org/10.1016/j.msec.2019.110273	Single-atom	Cu-nanoflower@gold nanoparticles-GO NFs
3251	20	In Situ Polymerized Hollow Mesoporous Organosilica Biocatalysis Nanoreactor for Enhancing ROS‐Mediated Anticancer Therapy	https://doi.org/10.1002/adfm.201907716	Others	hollow mesoporous organosilica nanoparticle(HMON)HMON-Au@Cu-TA
3252	21	Size-controllable Fe-N/C single-atom nanozyme with exceptional oxidase-like activity for sensitive detection of alkaline phosphatase	https://doi.org/10.1016/j.snb.2019.127511	Single-atom	Fe-N/C single-atom nanozyme(Fe-N/C)
3253	22	Nano-Biotechnology in Agriculture: Use of Nanomaterials to Promote Plant Growth and Stress Tolerance	https://doi.org/10.1021/acs.jafc.9b06615		review
3254	23	MOF-derived Co3O4@ Co-Fe oxide double-shelled nanocages as multi-functional specific peroxidase-like nanozyme catalysts for chemo/biosensing and dye degradation	https://doi.org/10.1016/j.cej.2020.125130	Composite	Co3O4@Co-Fe oxide double-shelled nanocages (DSNCs)
3255	24	Solvent-Assisted Self-Assembly of a Metal–Organic Framework Based Biocatalyst for Cascade Reaction Driven Photodynamic Therapy	https://doi.org/10.1021/jacs.0c02497	Composite	core–shell UMOFs@Au NPs
3256	25	Emerging functional materials based on chemically designed molecular recognition	https://doi.org/10.1186/s42833-019-0007-1		review
3257	26	Metal–Organic Framework Derived Nanozymes in Biomedicine	https://doi.org/10.1021/acs.accounts.0c00268		review
3258	27	Cascade Reaction System Integrating Single-Atom Nanozymes with Abundant Cu Sites for Enhanced Biosensing	https://doi.org/10.1021/acs.analchem.9b05437	Single-atom	Cu-N-C SAzymes
3259	28	Recent development in rapid detection techniques for microorganism activities in food matrices using bio-recognition: A review	https://doi.org/10.1016/j.tifs.2019.11.007		review
3260	29	A Tailored Multifunctional Anticancer Nanodelivery System for Ruthenium‐Based Photosensitizers: Tumor Microenvironment Adaption and Remodeling	https://doi.org/10.1002/advs.201901992	Composite	PDA‐Pt‐CD@RuFc NPs
3261	30	Gold nanomaterials as key suppliers in biological and chemical sensing, catalysis, and medicine	https://doi.org/10.1016/j.bbagen.2019.129435	Metal	review
3262	31	High peroxidase-like activity realized by facile synthesis of FeS2 nanoparticles for sensitive colorimetric detection of H2O2 and glutathione	https://doi.org/10.1016/j.bios.2019.111983	Sulfide	FeS2 nanoparticles
3263	32	Au2Pt-PEG-Ce6 nanoformulation with dual nanozyme activities for synergistic chemodynamic therapy/phototherapy	https://doi.org/10.1016/j.biomaterials.2020.120093	Multi-metal	Au2Pt
3264	33	An Enzyme‐Mimicking Single‐Atom Catalyst as an Efficient Multiple Reactive Oxygen and Nitrogen Species Scavenger for Sepsis Management	https://doi.org/10.1002/anie.201912182	Single-atom	nitrogen‐doped carbon‐supported atomically dispersed Co‐porphyrin centers (Co/PMCS)
3265	34	Ferritins as natural and artificial nanozymes for theranostics	https://doi.org/10.7150/thno.39827	Others	Review
3266	35	Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases	https://doi.org/10.1038/s41467-020-16544-7	Metal oxide	ultrasmall Cu5.4O nanoparticles (Cu5.4O USNPs)
3267	36	Oxygen-Vacancy-Enhanced Peroxidase-like Activity of Reduced Co3O4 Nanocomposites for the Colorimetric Detection of H2O2 and Glucose	https://doi.org/10.1021/acs.inorgchem.9b03512	Metal oxide	novel reduced Co3O4 nanoparticles (R-Co3O4)
3268	37	Recent advances in MOF-based nanoplatforms generating reactive species for chemodynamic therapy	https://doi.org/10.1039/d0dt01882a	MOF	Review
3269	38	Integrated cascade nanozyme catalyzes in vivo ROS scavenging for anti-inflammatory therapy	https://doi.org/10.1126/sciadv.abb2695	Composite	an integrated SOD/CAT mimetic cascade nanozyme (designated as Pt@PCN222-Mn) by introducing an SOD-like moiety of Mn(III) porphyrin and a CAT-like Pt NP within a nanoscale Zr-based MOF, PCN222
3270	39	A Porous Au@Rh Bimetallic Core–Shell Nanostructure as an H2O2‐Driven Oxygenerator to Alleviate Tumor Hypoxia for Simultaneous Bimodal Imaging and …	https://doi.org/10.1002/adma.202001862	Multi-metal	a new bimetallic and biphasic Rh-based core–shell nanosystem (Au@Rh-ICG-CM)
3271	40	One-pot bottom-up fabrication of a 2D/2D heterojuncted nanozyme towards optimized peroxidase-like activity for sulfide ions sensing	https://doi.org/10.1016/j.snb.2019.127565	Composite	MoS2/g-C3N4 heterojuncted nanosheets (MoS2/g-C3N4 HNs).
3272	41	Nanozymes: created by learning from nature	https://doi.org/10.1007/s11427-019-1570-7		review
3273	42	ROS-responsive nano-drug delivery system combining mitochondria-targeting ceria nanoparticles with atorvastatin for acute kidney injury	https://doi.org/10.7150/thno.40395	Composite	Ceria nanoparticles were modified with triphenylphosphine (TCeria NPs), followed by coating with ROS-responsive organic polymer (mPEG-TK-PLGA) and loaded atorvastatin (Atv/PTP-TCeria NPs)
3274	43	Multifunctional magnetic iron oxide nanoparticles: an advanced platform for cancer theranostics	https://doi.org/10.7150/thno.42564		review
3275	44	Biomimetic Platinum Nanozyme Immobilized on 2D Metal–Organic Frameworks for Mitochondrion-Targeting and Oxygen Self-Supply Photodynamic Therapy	https://doi.org/10.1021/acsami.9b14958	Composite	a new two-dimensional (2D)metal−organic framework, Sm-tetrakis(4-carboxyphenyl)porphyrin (TCPP) nanosheets,by assembling transition metal ions (Sm3+) and PSs (TCPP), on which the catalase (CAT)-mimicking platinum nanozymes were then in situ grown for sufficient oxygen supply during PDT
3276	45	A Dual Purpose Strategy to Endow Gold Nanoclusters with Both Catalysis Activity and Water Solubility	https://doi.org/10.1021/jacs.9b11017	Composite	a novel adamantanethiolateprotected Au40(S-Adm)22 nanocluster was synthesized, bound with γ-CD-MOF
3277	46	Metal‐Nitrogen‐Doped Carbon Materials as Highly Efficient Catalysts: Progress and Rational Design	https://doi.org/10.1002/advs.202001069		review
3278	47	Copper tannic acid coordination nanosheet: a potent nanozyme for scavenging ROS from cigarette smoke	https://doi.org/10.1002/smll.201902123	Composite	a novel copper tannic acid coordination (CuTA) nanozyme
3279	48	Densely Isolated FeN4 Sites for Peroxidase Mimicking	https://doi.org/10.1021/acscatal.0c01647	Carbon	Fe-NC nanozymes
3280	49	Hypoxia-tropic nanozymes as oxygen generators for tumor-favoring theranostics	https://doi.org/10.1016/j.biomaterials.2019.119635	Composite	hypoxia-tropic nanozyme as oxygen generator (OGzyme) by the biomimetic synthesis of MnO2 nanoparticles inside the hollow cavity of FTn
3281	50	Stereospecific interactions between chiral inorganic nanomaterials and biological systems	https://doi.org/10.1039/D0CS00093K		review
3282	51	Emerging Multifunctional Single-Atom Catalysts/Nanozymes	https://doi.org/10.1021/acscentsci.0c00512	Single-atom	review
3283	52	Nanoenzyme-Reinforced Injectable Hydrogel for Healing Diabetic Wounds Infected with Multidrug Resistant Bacteria	https://doi.org/10.1021/acs.nanolett.0c01371	Composite	EPL-coated MnO2 nanosheets (EM) and insulin-encapsulated aldehyde Pluronic F127 (FCHO) micelles
3284	53	Recent advances in the design of colorimetric sensors for environmental monitoring	https://doi.org/10.1039/D0EN00449A	unsure	review
3285	54	Electrochemical generation of Fe3C/N-doped graphitic carbon nanozyme for efficient wound healing in vivo	https://doi.org/10.1016/j.carbon.2019.11.093	Carbon	Fe3C/N-doped graphitic carbon nanomaterial (Fe3C/N–C)
3286	55	Gold nanozyme: Biosensing and therapeutic activities	https://doi.org/10.1016/j.msec.2019.110422	Metal	review
3287	56	Biomimetic metal-organic frameworks mediated hybrid multi-enzyme mimic for tandem catalysis	https://doi.org/10.1016/j.cej.2019.122758	MOF	MOF-546(Fe)
3288	57	Electrochemical glucose sensors in diabetes management: an updated review (2010–2020)	https://doi.org/10.1039/D0CS00304B	unsure	review
3289	58	Catalytic chemistry of iron-free Fenton nanocatalysts for versatile radical nanotherapeutics	https://doi.org/10.1039/C9MH01565E	unsure	review
3290	59	Single-atom nanozymes: A rising star for biosensing and biomedicine	https://doi.org/10.1016/j.ccr.2020.213376	Single-atom	review
3291	60	Cu2MoS4/Au Heterostructures with Enhanced Catalase‐Like Activity and Photoconversion Efficiency for Primary/Metastatic Tumors Eradication by Phototherapy …	https://doi.org/10.1002/smll.201907146	Composite	Cu2MoS4 (CMS)/Au，Cu2MoS4 (CMS)/Au heterostructures are constructed by depositing plasmonic Au nanoparticles onto CMS nanosheets
3292	61	Dual responsive magnetic Fe3O4-TiO2/graphene nanocomposite as an artificial nanozyme for the colorimetric detection and photodegradation of pesticide in an aqueous medium	https://doi.org/10.1016/j.jhazmat.2019.121516	Composite	Fe3O4-TiO2/graphene nanocomposite
3293	62	Ultrasmall gold nanoparticles in cancer diagnosis and therapy	https://doi.org/10.7150/thno.42471	Metal	review
3294	63	Promoting Active Sites in MOF-Derived Homobimetallic Hollow Nanocages as a High-Performance Multifunctional Nanozyme Catalyst for Biosensing and Organic Pollutant Degradation	https://doi.org/10.1021/acsami.9b20275	Others	Co-based homobimetallic hollow nanocages
3295	64	Enhanced peroxidase-like activity of hierarchical MoS2-decorated N-doped carbon nanotubes with synergetic effect for colorimetric detection of H2O2 and ascorbic acid	https://doi.org/10.1016/j.cclet.2019.09.037	Composite	MoS2 decorated N-doped carbon nanotubes (NCNTs@MoS2) hybrid composites
3296	65	Fruit waste (Pulp) decorated CuO NFs as promising platform for enhanced catalytic response and its peroxidase mimics evaluation	https://doi.org/10.1016/j.arabjc.2019.09.007	Composite	carbon enriched mesoporous material (CuO NFs@MP) using fruit waste
3297	66	Colorimetric quantification and discrimination of phenolic pollutants based on peroxidase-like Fe3O4 nanoparticles	https://doi.org/10.1016/j.snb.2019.127225	Metal oxide	Fe3O4 NPs
3298	67	Nanozyme-based catalytic theranostics	https://doi.org/10.1039/c9ra09021e	Others	Review
3299	68	Nanomagnet-Silica Nanoparticles Decorated with Au@ Pd for Enhanced Peroxidase-Like Activity and Colorimetric Glucose Sensing	https://doi.org/10.1021/acsami.9b15123	Composite	Nanomagnet-silica shell (Fe3O4@SiO2) decorated with Au@Pd nanoparticles (NPs)
3300	69	Nanoporous core@ shell particles: Design, preparation, applications in bioadsorption and biocatalysis	https://doi.org/10.1016/j.nantod.2019.100834	Others	Review
3301	70	Application of nanotechnology for enhancing photodynamic therapy via ameliorating, neglecting, or exploiting tumor hypoxia	https://doi.org/10.1002/viw2.6	Others	Review
3302	71	Bimetallic nanoparticles decorated hollow nanoporous carbon framework as nanozyme biosensor for highly sensitive electrochemical sensing of uric acid	https://doi.org/10.1016/j.bios.2019.111869	Composite	gold/cobalt (Au/Co) bimetallic nanoparticles (NPs) decorated hollow nanoporous carbon framework (Au/Co@HNCF)
3303	72	Light-activated nanozymes: catalytic mechanisms and applications	https://doi.org/10.1039/C9NR10822J	Others	Review
3304	73	Bienzymatic synergism of vanadium oxide nanodots to efficiently eradicate drug-resistant bacteria during wound healing in vivo	https://doi.org/10.1016/j.jcis.2019.09.040	Metal oxide	vanadium oxide nanodots (VOxNDs)
3305	74	Comprehensive Review on Current Interventions, Diagnostics, and Nanotechnology Perspectives against SARS-CoV-2	https://doi.org/10.1021/acs.bioconjchem.0c00323	Others	Review
3306	75	Prussian Blue modified boron-doped diamond interfaces for advanced H2O2 electrochemical sensors	https://doi.org/10.1016/j.electacta.2020.135924	Composite	boron-doped diamond (BDD) electrodes modified with Prussian Blue (PB)
3307	76	Paper based colorimetric detection of miRNA-21 using Ag/Pt nanoclusters	https://doi.org/10.1016/j.saa.2019.117529	Composite	DNA-templated Ag/Pt nanoclusters (DNA-Ag/Pt NCs)
3308	77	Mitochondria-targeted TPP-MoS2 with dual enzyme activity provides efficient neuroprotection through M1/M2 microglial polarization in an Alzheimer's disease model	https://doi.org/10.1016/j.biomaterials.2019.119752	Composite	TPP-conjugated 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] functionalized molybdenum disulfide quantum dots (TPP-MoS2 QDs)
3309	78	Dramatically Enhanced Immunochromatographic Assay Using Cascade Signal Amplification for Ultrasensitive Detection of Escherichia coli O157:H7 in Milk	https://doi.org/10.1021/acs.jafc.9b07076	Metal	AuNP-ICA platform
3310	79	Nanozyme-based electrochemical biosensors for disease biomarker detection	https://doi.org/10.1039/D0AN00558D	Others	Review
3311	80	State-of-the-art iron-based nanozymes for biocatalytic tumor therapy	https://doi.org/10.1039/C9NH00577C	Others	Review
3312	81	The importance of nanoscale confinement to electrocatalytic performance	https://doi.org/10.1039/C9SC05611D	Multi-metal	Surfactant covered Pt–Ni nanozyme nanoparticles, with Ni etched from the nanoparticles, possess a nanoscale channel in which the active sites for electrocatalysis of oxygen reduction are located
3313	82	A metal-free nanozyme-activated prodrug strategy for targeted tumor catalytic therapy	https://doi.org/10.1016/j.nantod.2020.100935	Carbon	phosphorous and nitrogen dual-doped porous hollow carbon sphere
3314	83	Nanoparticles-mediated reoxygenation strategy relieves tumor hypoxia for enhanced cancer therapy	https://doi.org/10.1016/j.jconrel.2019.12.028		Review
3315	84	Bifunctionalized novel Co-V MMO nanowires: Intrinsic oxidase and peroxidase like catalytic activities for antibacterial application	https://doi.org/10.1016/j.apcatb.2019.118256	Composite	composite of Co3V2O8 uniform dispersing among Co3O4
3316	85	Artificial nanozyme based on platinum nanoparticles anchored metal-organic frameworks with enhanced electrocatalytic activity for detection of	https://doi.org/10.1016/j.bios.2019.111838	Composite	ultra-small Pt nanoparticles (Pt NPs) grown on nanoscale metalloporphyrin metal organic frameworks
3317	86	Biosafety materials: an emerging new researchdirection of materials science from theCOVID-19 outbreak	https://doi.org/10.1039/d0qm00255k		Review
3318	87	MOF-encapsulated nanozyme enhanced siRNA combo: Control neural stem cell differentiation and ameliorate cognitive impairments in Alzheimer's	https://doi.org/10.1016/j.biomaterials.2020.120160	Composite	integrating antioxidative nanozymes (ceria) into metal-organic frameworks (MOF)
3319	88	Biosensor Nanoengineering: Design, Operation, and Implementation for Biomolecular Analysis	https://doi.org/10.1016/j.sintl.2020.100040		Review
3320	89	Polymer-based bioorthogonal nanocatalysts for the treatment of bacterial biofilms	https://doi.org/10.1021/jacs.0c01758	Composite	self-assembled polymer nanoparticles engineered to encapsulate lipophilic transition metal catalysts
3321	90	Nanozyme sensor arrays based on heteroatom-doped graphene for detecting pesticides	https://doi.org/10.1021/acs.analchem.9b05110	Carbon	heteroatom-doped graphene
3322	91	Colorimetric/SERS dual-mode detection of mercury ion via SERS-Active peroxidase-like Au@ AgPt NPs	https://doi.org/10.1016/j.snb.2020.127849	Multi Metal	Au@AgPt
3323	92	Ultrasmall Rhodium Nanozyme with RONS Scavenging and Photothermal Activities for Anti-Inflammation and Antitumor Theranostics of Colon Diseases	https://doi.org/10.1021/acs.nanolett.9b05035	Metal	Rhodium
3324	93	Frontiers in electrochemical enzyme based biosensors for food and drug analysis	https://doi.org/10.1016/j.trac.2020.115809		Review
3325	94	Building block and rapid synthesis of catecholamines-inorganic nanoflowers with their peroxidase-mimicking and antimicrobial activities	https://doi.org/10.1038/s41598-020-59699-5	Other	Cu2+-catecholamines incorporated nanoflowers
3326	95	Colorimetric Assay of Bacterial Pathogens Based on Co3O4 Magnetic Nanozymes Conjugated with Specific Fusion Phage Proteins and Magnetophoretic …	https://doi.org/10.1021/acsami.9b23101	Metal oxide	Co3O4
3327	96	Using target-specific aptamers to enhance the peroxidase-like activity of gold nanoclusters for colorimetric detection of tetracycline antibiotics	https://doi.org/10.1016/j.talanta.2019.120342	Metal	AuNCs
3328	97	‘Artificial peroxidase’nanozyme–enzyme based lactate biosensor	https://doi.org/10.1016/j.talanta.2019.120393	Other	Prussian Blue
3329	98	Luminescence-Sensing Tb-MOF Nanozyme for the Detection and Degradation of Estrogen Endocrine Disruptors	https://doi.org/10.1021/acsami.9b22537	MOF	Tb-OBBA-Hemin
3330	99	Bioinspired chemistry at MOF secondary building units	https://doi.org/10.1039/C9SC06418D		Review
3331	100	Manganese‐Based Functional Nanoplatforms: Nanosynthetic Construction, Physiochemical Property, and Theranostic Applicability	https://doi.org/10.1002/adfm.201907066		Review
3332	101	Cerium oxide nanoparticles attenuate oxidative stress and inflammation in the liver of Diethylnitrosamine-treated mice	https://doi.org/10.1007/s12011-019-01696-5	Metal oxide	poly acrylic acid polymer coated cerium oxide nanoparticles
3333	102	Engineered defects in cerium oxides: tuning chemical reactivity for biomedical, environmental, & energy applications	https://doi.org/10.1039/D0NR01203C	Metal oxide	Review
3334	103	Nanoceria-Templated Metal Organic Frameworks with Oxidase-Mimicking Activity Boosted by Hexavalent Chromium	https://doi.org/10.1021/acs.analchem.9b05593	MOF	cerium oxide nanorod templated metal organic frameworks (CeO2NRs-MOF)
3335	104	New insights into the degradation of synthetic pollutants in contaminated environments	https://doi.org/10.1016/j.chemosphere.2020.128827	Others	Review
3336	105	A cerium-based MOFzyme with multi-enzyme-like activity for the disruption and inhibition of fungal recolonization	https://doi.org/10.1039/d0tb00894j	MOF	A cerium-based metal–organic framework (Ce-MOF, denoted as AU-1) was synthesized using a solvothermal method by employing 4,40,400-nitrilotribenzoic acid (H3NTB) as the linker and cerium clusters as the metal center
3337	106	Immunomodulation‐Enhanced Nanozyme‐Based Tumor Catalytic Therapy	https://doi.org/10.1002/adma.202003563	Composite	TGF-β inhibitor (TI)-loaded PEGylated iron manganese silicate nanoparticles (IMSN) (named as IMSN-PEG-TI) are constructed to trigger the therapeutic modality.
3338	107	Protein‐protected metal nanoclusters: An emerging ultra‐small nanozyme	https://doi.org/10.1002/wnan.1602	Metal	Review
3339	108	Immobilized Glucose Oxidase on Boronic Acid-Functionalized Hierarchically Porous MOF as an Integrated Nanozyme for One-Step Glucose Detection	https://doi.org/10.1021/acssuschemeng.9b07631	MOF	In this study, a boronic acid-functionalized hierarchically porous MIL-88B (HP-MIL-88B-BA) was prepared as an efficient immobilization matrix for glucose oxidase (GOx).
3340	109	Specific “Unlocking” Nanozyme‐based Butterfly Effect for Breaking the Evolutionary Fitness of Chaotic Tumor	https://doi.org/10.1002/anie.201916142	Metal oxide	Herein, we demonstrate for the first time that iridium oxide nanoparticles (IrOx) possess acid-activated oxidase and peroxidase-like functions and wide pH-dependent catalase-like properties.
3341	110	Two‐Dimensional Tin Selenide (SnSe) Nanosheets Capable of Mimicking Key Dehydrogenases in Cellular Metabolism	https://doi.org/10.1002/ange.201913035	Others	two-dimension (2D) SnSe is capable of mimicking native dehydrogenases to efficiently catalyze hydrogen transfer from 1-(R)-2-(R')-ethanol groups.
3342	111	Virus-Like Fe3O4@Bi2S3 Nanozymes with Resistance-Free Apoptotic Hyperthermia-Augmented Nanozymitic Activity for Enhanced Synergetic Cancer Therapy	https://doi.org/10.1021/acsami.9b20661	Composite	Fe3O4@Bi2S3 nanocatalysts (F-BS NCs)
3343	112	Synthesis of Cerium Oxide Nanoparticles Using Various Methods: Implications for Biomedical Applications	https://doi.org/10.3390/nano10020242	Metal oxide	review
3344	113	Relationship Between Sweat and Blood Lactate Levels During Exhaustive Physical Exercise	https://doi.org/10.1002/celc.201901703	MOF	Prussian Blue
3345	114	Platinum-carbon-integrated nanozymes for enhanced tumor photodynamic and photothermal therapy	https://doi.org/10.1039/D0NR02800B	Composite	a platinum-carbon-integrated nanozyme (Pt-carbon nanozyme)
3346	115	Non-Enzymatic Amperometric Glucose Sensor Based on Carbon Nanodots and Copper Oxide Nanocomposites Electrode	https://doi.org/10.3390/s20030808	Composite	carbon nanodots (C-dots) and copper oxide (CuO) nanocomposites (CuO-C-dots)
3347	116	Metal-organic framework-based engineered materials—Fundamentals and applications	https://doi.org/10.3390/molecules25071598	MOF	Review article
3348	117	Ultrasensitive amperometric immunosensor for the prostate specific antigen by exploiting a Fenton reaction induced by a metal-organic framework nanocomposite of type Au/Fe-MOF …	https://doi.org/10.1007/s00604-019-4075-4	Composite	Au/Fe-MOF
3349	118	Colorimetric determination of the early biomarker hypoxia-inducible factor-1 alpha (HIF-1α) in circulating exosomes by using a gold seed-coated with aptamer-functionalized Au …	https://doi.org/10.1007/s00604-019-4035-z	Composite	Au@Au-aptamer:the aptamer modified on the AuNPs surface, a golden shell with a larger surface area formed by depositing on the surface of AuNPs-aptamer
3350	119	Cobalt-based metal organic frameworks: a highly active oxidase-mimicking nanozyme for fluorescence “turn-on” assays of biothiol	https://doi.org/10.1039/C9CC06840F	MOF	Co-based metal organic frameworks (ZIF-67)
3351	120	Ultrasensitive electrochemical genosensor for detection of CaMV35S gene with Fe3O4-Au@ Ag nanoprobe	https://doi.org/10.1016/j.talanta.2019.120205	Composite	Au@Ag-loaded magnetic nanoparticles
3352	121	CeO2/C nanowire derived from a cerium (III) based organic framework as a peroxidase mimic for colorimetric sensing of hydrogen peroxide and for enzymatic sensing of glucose	https://doi.org/10.1007/s00604-019-4032-2	Composite	CeO2/C nanowires
3353	122	Recent progress of chemodynamic therapy-induced combination cancer therapy	https://doi.org/10.1016/j.nantod.2020.100946		Review article
3354	123	Bioinspired Copper Single‐Atom Catalysts for Tumor Parallel Catalytic Therapy	https://doi.org/10.1002/adma.202002246	Single-atom	a bioinspired hollow N‐doped carbon sphere doped with a single‐atom copper species (Cu‐HNCS)
3355	124	Intelligent nanoenzyme for T1-weighted MRI guided theranostic applications	https://doi.org/10.1016/j.cej.2019.123609	Composite	PPy@MnO2-BSA (bovine serum albumin (BSA)-modified manganese dioxide (MnO2)/polypyrrole (PPy))
3356	125	Ag@ Au core/shell triangular nanoplates with dual enzyme-like properties for the colorimetric sensing of glucose	https://doi.org/10.1016/j.cclet.2019.10.011	Composite	Ag@Au core/shell triangular nanoplates (TNPs)
3357	126	Colorimetric immunoassays based on pyrroloquinoline quinone-catalyzed generation of Fe (II)-ferrozine with tris (2-carboxyethyl) phosphine as the reducing reagent	https://doi.org/10.1016/j.snb.2019.127571	Composite	pyrroloquinoline quinone (PQQ) promoted the reduction of Fe(III)-ferrozine by tris(2-carboxyethyl)phosphine (TCEP)
3358	127	Cascade catalytic nanoplatform for enhanced starvation and sonodynamic therapy	https://doi.org/10.1080/1061186X.2019.1641507	Composite	GOx modified the mesoporous MnO2 NPs loaded with hematoporphyrin monomethyl ether (HMME)
3359	128	Smartphone colorimetric determination of hydrogen peroxide in real samples based on B, N, and S co-doped carbon dots probe	https://doi.org/10.1007/s00216-019-02284-1	Carbon	B, N, and S co-doped carbon dots (BNS-CDs)
3360	129	Biomass-derived hierarchically porous CoFe-LDH/CeO2hybrid with peroxidase-like activity for colorimetric sensing of H2O2 and glucose	https://doi.org/10.1016/j.jallcom.2019.152276	Composite	Biomass-derived hierarchically porous CoFe-LDH (layered double hydroxides)/CeO2 hybrid
3361	130	Catalytic processing in ruthenium-based polyoxometalate coacervate protocells	https://doi.org/10.1038/s41467-019-13759-1	Composite	polymer/nucleotide coacervate micro-droplets are reconfigured into membrane-bounded polyoxometalate coacervate vesicles (PCVs) in the presence of a bio-inspired Ru-based polyoxometalate catalyst to produce synzyme protocells (Ru4PCVs)
3362	131	Biological, biomedical and pharmaceutical applications of cerium oxide	https://doi.org/10.1016/B978-0-12-815661-2.00008-6	Metal oxide	review
3363	132	Insight into the efficiency of oxygen introduced photodynamic therapy (PDT) and deep PDT against cancers with various assembled nanocarriers	https://doi.org/10.1002/wnan.1583		review
3364	133	Antioxidant properties of gold nanozyme: A review	https://doi.org/10.1016/j.molliq.2019.112004		review
3365	134	A covalent triazine framework as an oxidase mimetic in the luminol chemiluminescence system: Application to the determination of the antioxidant rutin	https://doi.org/10.1007/s00604-019-4058-5	COF	Covalent triazine frameworks (CTF–1)
3366	135	Metal-organic frameworks and their derivatives as signal amplification elements for electrochemical sensing	https://doi.org/10.1016/j.ccr.2020.213520		review
3367	136	Structure and activity of nanozymes: Inspirations for de novo design of nanozymes	https://doi.org/10.1016/j.mattod.2020.08.020	Others	Review
3368	137	A peroxidase-mimicking Zr-based MOF colorimetric sensing array to quantify and discriminate phosphorylated proteins	https://doi.org/10.1016/j.aca.2020.04.073	MOF	Zr-based MOF
3369	138	Ru@ CeO2 yolk shell nanozymes: Oxygen supply in situ enhanced dual chemotherapy combined with photothermal therapy for orthotopic/subcutaneous colorectal cancer	https://doi.org/10.1016/j.biomaterials.2020.119923	Composite	hollow Ru@CeO2 yolk shell nanozymes
3370	139	Electrochemical biosensor based on gold nanoflowers-encapsulated magnetic metal-organic framework nanozymes for drug evaluation with in-situ monitoring of H2O2 released from …	https://doi.org/10.1016/j.snb.2020.127909	Composite	gold nanoflowers-encapsulated magnetic metal-organic framework nanozymes
3371	140	Solving the H2O2 by-product problem using a catalase-mimicking nanozyme cascade to enhance glycolic acid oxidase	https://doi.org/10.1016/j.cej.2020.124249	Others	Fe3+ and adenosine monophosphate coordination nanoparticles
3372	141	A novel fluorescence aptamer biosensor for trace Pb (II) based on gold-doped carbon dots and DNAzyme synergetic catalytic amplification	https://doi.org/10.1016/j.jlumin.2020.117056	Composite	Gold-doped carbon dots
3373	142	Chiral carbon dots mimicking topoisomerase I to enantioselectively mediate topological rearrangement of supercoiled DNA.	https://doi.org/10.1002/anie.202002904	Carbon	chiral carbon dots
3374	143	Electrochemical DNA sensor for inorganic mercury (II) ion at attomolar level in dairy product using Cu (II)-anchored metal-organic framework as mimetic catalyst	https://doi.org/10.1021/acs.analchem.8b03969	Others	dinitrophenylhydrazine
3375	144	Zero-Dimensional/Two-Dimensional AuxPd100–x Nanocomposites with Enhanced Nanozyme Catalysis for Sensitive Glucose Detection	https://doi.org/10.1021/acsami.9b21621	Metal	two-dimensional (2D) Pd nanosheet (NS)-supported zero-dimensional (0D) Au nanoparticles
3376	145	Highly sensitive photoelectrochemical detection of bleomycin based on Au/WS2 nanorod array as signal matrix and Ag/ZnMOF nanozyme as multifunctional amplifier	https://doi.org/10.1016/j.bios.2019.111875	Composite	silver nanoparticles/flake-like zinc metal-organic framework (Ag/ZnMOF) nanozyme
3377	146	On the origin of microbial magnetoreception	https://doi.org/10.1093/nsr/nwz065	Others	Review
3378	147	Robust magnetic laccase-mimicking nanozyme for oxidizing o-phenylenediamine and removing phenolic pollutants	https://doi.org/10.1016/j.jes.2019.07.008	Composite	Fe3O4@Cu/GMP (guanosine 5′-monophosphate)
3379	148	Microwave-assisted synthesis of carbon dots as reductant and stabilizer for silver nanoparticles with enhanced-peroxidase like activity for colorimetric determination of …	https://doi.org/10.1007/s00604-019-4098-x	Composite	carbon silver nano-assembly
3380	149	Highly Selective Fluorescent Sensing of Phosphite through Recovery of Poisoned Nickel Oxide Nanozyme	https://doi.org/10.1021/acs.analchem.9b04736	Metal oxide	Nickel oxide
3381	150	Co3O4@ β-cyclodextrin with synergistic peroxidase-mimicking performance as a signal magnification approach for colorimetric determination of ascorbic acid	https://doi.org/10.1016/j.snb.2019.127106	Metal oxide	Co3O4@β-cyclodextrin nanoparticles
3382	151	Biomimetic nanoscale metal–organic framework harnesses hypoxia for effective cancer radiotherapy and immunotherapy	https://doi.org/10.1039/D0SC01949F	MOF	Hf-DBP-Fe
3383	152	Nanozymes and aptamer-based biosensing	https://doi.org/10.1016/j.mset.2019.08.007	Others	Review
3384	153	Applications of nanozymes in the environment	https://doi.org/10.1039/C9EN01089K	Others	Review
3385	154	A robust hybrid nanozyme@ hydrogel platform as a biomimetic cascade bioreactor for combination antitumor therapy	https://doi.org/10.1039/C9BM01837A	Composite	hybrid nanozyme/hydrogel system containing Prussian blue (PB) nanoparticles and glucose oxidase (GOD)
3386	155	Ultrasmall theranostic nanozymes to modulate tumor hypoxia for augmenting photodynamic therapy and radiotherapy	https://doi.org/10.1039/C9BM01742A	Metal	indocyanine green (ICG)-loaded ultrasmall gold nanoclusters
3387	156	An Au@ NH 2-MIL-125 (Ti)-based multifunctional platform for colorimetric detections of biomolecules and Hg2+	https://doi.org/10.1039/c9tb02183c	Composite	Au@NH2-MIL-125(Ti)
3388	157	GSH‐Depleted Nanozymes with Hyperthermia‐Enhanced Dual Enzyme‐Mimic Activities for Tumor Nanocatalytic Therapy	https://doi.org/10.1002/adma.202002439.	Composite	PEG/Ce-Bi@DMSN
3389	158	Ag/Pd bimetal nanozyme with enhanced catalytic and photothermal effects for ROS/hyperthermia/chemotherapy triple-modality antitumor therapy	https://doi.org/10.1016/j.cej.2020.125438	Multi-metal	AgPd@BSA/DOX
3390	159	Using bimetallic Au@ Pt nanozymes as a visual tag and as an enzyme mimic in enhanced sensitive lateral-flow immunoassays: Application for the detection of streptomycin	https://doi.org/10.1016/j.aca.2020.06.009	Multi-metal	Au@Pt
3391	160	The Fe‐N‐C Nanozyme with Both Accelerated and Inhibited Biocatalytic Activities Capable of Accessing Drug–Drug Interactions	https://doi.org/10.1002/ange.202003949	Single-atom	Fe-N-C
3392	161	Epitaxially Strained CeO2/Mn3O4 Nanocrystals as an Enhanced Antioxidant for Radioprotection	https://doi.org/10.1002/adma.202001566	Composite	CeO2/Mn3O4 Nanocrystals
3393	162	A mitochondria-targeting magnetothermogenic nanozyme for magnet-induced synergistic cancer therapy	https://doi.org/10.1016/j.biomaterials.2020.120079	Composite	Ir@MnFe2O4 NPs
3394	163	A Review on Metal Nanozyme-Based Sensing of Heavy Metal Ions: Challenges and Future Perspectives	https://doi.org/10.1016/j.jhazmat.2020.123397		Review
3395	164	Target-Driven Nanozyme Growth in TiO2 Nanochannels for Improving Selectivity in Electrochemical Biosensing	https://doi.org/10.1021/acs.analchem.0c01815	MOF	Inspired by the photocatalytic activity of TiO2, a strategy was designed involving the in situ growth of POD-like nanozyme Prussian blue30 nanoparticles (PBNPs) in nanochannels.
3396	165	Dual modality sensor using liposome-based signal amplification technique for ultrasensitive norovirus detection	https://doi.org/10.1016/j.bios.2020.112169	Metal oxide	V2O5 nanoparticles-encapsulated liposomes (VONP-LPs)
3397	166	Carbon quantum dots originated from chicken blood as peroxidase mimics for colorimetric detection of biothiols	https://doi.org/10.1016/j.jphotochem.2020.112529	Carbon	Carbon quantum dots (CQDs) from chicken blood
3398	167	In Situ Fabrication of Ultrasmall Gold Nanoparticles/2D MOFs Hybrid as Nanozyme for Antibacterial Therapy	https://doi.org/10.1002/smll.202000553	Composite	ultrasmall Au nanoparticles (UsAuNPs) are grown on ultrathin 2D metal–organic frameworks (MOFs) via in situ reduction
3399	168	A label-free fluorescence biosensor based on a bifunctional MIL-101 (Fe) nanozyme for sensitive detection of choline and acetylcholine at nanomolar level	https://doi.org/10.1016/j.snb.2020.128021	MOF	MIL-101(Fe)
3400	169	Thermally gated bio-orthogonal nanozymes with supramolecularly confined porphyrin catalysts for antimicrobial uses	https://doi.org/10.1016/j.chempr.2020.01.015	Composite	FeTPP assemblies within AuTTMA monolayer
3401	170	Bioelectrofuel synthesis by nanoenzymes: Novel alternatives to conventional enzymes	https://doi.org/10.1016/j.tibtech.2020.02.011		Review
3402	171	Heparin-platinum nanozymes with enhanced oxidase-like activity for the colorimetric sensing of isoniazid	https://doi.org/10.1016/j.talanta.2019.120707	Metal	heparin sodium stabilized platinum nanoparticles (HS-PtNPs)
3403	172	Integration of Fe3O4 with Bi2S3 for Multi-Modality Tumor Theranostics	https://doi.org/10.1021/acsami.0c05088	Composite	Fe3O4@PDA@BSA-Bi2S3
3404	173	Colorimetric acid phosphatase sensor based on MoO3 nanozyme	https://doi.org/10.1016/j.aca.2020.01.035	Metal oxide	molybdenum oxide nanoparticles (MoO3 NPs).
3405	174	Iridium/ruthenium nanozyme reactors with cascade catalytic ability for synergistic oxidation therapy and starvation therapy in the treatment of breast cancer	https://doi.org/10.1016/j.biomaterials.2020.119848	Composite	IrRu-GOx@PEG NPs
3406	175	A colorimetric strategy for ascorbic acid sensing based on the peroxidase-like activity of core-shell Fe3O4/CoFe-LDH hybrid	https://doi.org/10.1016/j.colsurfb.2019.110742	Composite	Fe3O4/CoFe-LDH
3407	176	Plasma-Assisted Controllable Doping of Nitrogen into MoS2 Nanosheets as Efficient Nanozymes with Enhanced Peroxidase-Like Catalysis Activity	https://doi.org/10.1021/acsami.0c01789	Composite	resulting N-doped MoS2 nanosheets
3408	177	Nanozymes for medical biotechnology and its potential applications in biosensing and nanotherapeutics	https://doi.org/10.1007/s10529-020-02795-3	Others	review
3409	178	Biogenic synthesis of AuPd nanocluster as a peroxidase mimic and its application for colorimetric assay of acid phosphatase	https://doi.org/10.1016/j.colsurfa.2020.124444	Multi-metal	AuPt nanoclusters (Au1Pd5 NCs)
3410	179	Nanozyme-Modified Metal–Organic Frameworks with Multienzymes Activity as Biomimetic Catalysts and Electrocatalytic Interfaces	https://doi.org/10.1021/acsami.9b23147	MOF	ultrasmall Pt nanoparticles (Pt NPs) were loaded on the surface of PMOF(Fe) to form Pt@PMOF(Fe)
3411	180	Antioxidants and Nanotechnology: Promises and Limits of Potentially Disruptive Approaches in the Treatment of Central Nervous System Diseases	https://doi.org/10.1002/adhm.201901589	Others	review
3412	181	Hemin@carbon dot hybrid nanozymes with peroxidase mimicking properties for dual (colorimetric and fluorometric) sensing of hydrogen peroxide, glucose and xanthine	https://doi.org/10.1007/s00604-019-4103-4	Composite	hemin@carbon dot hybrid nanozymes (hemin@CD)
3413	182	BiO2–x Nanosheets as Radiosensitizers with Catalase-Like Activity for Hypoxia Alleviation and Enhancement of the Radiotherapy of Tumors	https://doi.org/10.1021/acs.inorgchem.9b03280	Metal oxide	ultrathin BiO2–x nanosheets (NSs) modified with Tween 20 (T-BiO2–x NSs)
3414	183	Designing electrochemical interfaces based on nanohybrids of avidin functionalized-carbon nanotubes and ruthenium nanoparticles as peroxidase-like nanozyme with supramolecular recognition properties for site-specific anchoring of biotinylated residues	https://doi.org/10.1016/j.bios.2019.111764	Composite	GCE/MWCNTs-Av/RuNPs
3415	184	Colorimetric Detection of Nucleic Acids through Triplex-Hybridization Chain Reaction and DNA-Controlled Growth of Platinum Nanoparticles on Graphene Oxide	https://doi.org/10.1021/acs.analchem.9b04909	Composite	a DNA-controlled strategy for growth of Pt nanoparticles on graphene oxide (GO–PtNPs)
3416	185	Cerium oxide nanoparticles: properties, biosynthesis and biomedical application	https://doi.org/10.1039/D0RA04736H	Metal oxide	Review
3417	186	Remote-controlled multi-enzyme system for enhanced tumor therapy via dark/light relay catalysis	https://doi.org/10.1039/C9NH00583H	Composite	Membrane camouflaged and GOx loaded hollow mesoporous Prussian blue (mGPB)
3418	187	Recent developments of nanoenzyme-based colorimetric sensors for heavy metal detection and the interaction mechanism	https://doi.org/10.1039/D0AN00339E	Others	review
3419	188	Advanced nanotechnology for hypoxia-associated antitumor therapy	https://doi.org/10.1039/C9NR09071A	Others	review
3420	189	Highly sensitive colorimetric sensor for detection of iodine ions using carboxylated chitosan–coated palladium nanozyme	https://doi.org/10.1007/s00216-019-02270-7	Composite	carboxylated chitosan stabilized Pd nanoparticles (CC-PdNPs)
3421	190	Bioinspired Nanosponge for Salvaging Ischemic Stroke via Free Radical Scavenging and Self-Adapted Oxygen Regulating	https://doi.org/10.1021/acs.nanolett.9b04974	Composite	Mn3O4@nanoerythrocyte-T7, MNET
3422	191	Nanomaterials to relieve tumor hypoxia for enhanced photodynamic therapy	https://doi.org/10.1016/j.nantod.2020.100960	Others	review
3423	192	Conjugation of antibodies and aptamers on nanozymes for developing biosensors	https://doi.org/10.1016/j.bios.2020.112537	Others	review
3424	193	Green synthesis of allicin based hybrid nanoflowers with evaluation of their catalytic and antimicrobial activities	https://doi.org/10.1007/s10529-020-02877-2	Composite	The allicin (active ingredient of Allium sativum) and Cu2+ was acted as an organic and inorganic part, respectively for synthesis of the Cu-hNFs
3425	194	A sandwich ELISA-like detection of C-reactive protein in blood by citicoline-bovine serum albumin conjugate and aptamer-functionalized gold nanoparticles nanozyme	https://doi.org/10.1016/j.talanta.2020.121070	Composite	aptamer-functionalized gold nanoparticles (aptamer-AuNPs)
3426	195	Carbon dots-stabilized Cu4O3 for a multi-responsive nanozyme with exceptionally high activity	https://doi.org/10.1016/j.cej.2020.125045	Composite	A CDs-stabilized Cu4O3 nanozyme
3427	196	Oxidase-like MOF-818 Nanozyme with High Specificity for Catalysis of Catechol Oxidation	https://doi.org/10.1021/jacs.0c07273	MOF	MOF-818, catechol oxidase
3428	197	Group IV nanodots: newly emerging properties and application in biomarkers sensing	https://doi.org/10.1016/j.trac.2020.116007		Review
3429	198	Colorimetric ascorbic acid sensing from a synergetic catalytic strategy based on 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphyrin functionalized CuS nanohexahedrons with the enhanced peroxidase-like activity	https://doi.org/10.1016/j.colsurfa.2020.124855	Sulfide	TPyP-CuS, 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphyrin (TPyP) functionalized CuS nanohexahedrons
3430	199	Stimuli-Responsive Small-on-Large Nanoradiosensitizer for Enhanced Tumor Penetration and Radiotherapy Sensitization	https://doi.org/10.1021/acsnano.0c03094	Composite	disassembled small-on-large molybdenum disulfide/hafnium dioxide (MoS2/HfO2) dextran (M/H-D) nanoradiosensitizer.
3431	200	White Peroxidase‐Mimicking Nanozymes: Colorimetric Pesticide Assay without Interferences of O2 and Color	https://doi.org/10.1002/adfm.202001933	Metal oxide	GeO2
3432	201	Self-generation of oxygen and simultaneously enhancing photodynamic therapy and MRI effect: An intelligent nanoplatform to conquer tumor hypoxia for enhanced phototherapy	https://doi.org/10.1016/j.cej.2020.124624	Metal oxide	honeycomb MnO2
3433	202	Highly dispersed Pt nanoparticles on ultrasmall EMT zeolite: A peroxidase-mimic nanoenzyme for detection of H2O2 or glucose	https://doi.org/10.1016/j.jcis.2020.02.118	Composite	In this work, novel Pt/EMT nanocomposites were prepared by uniformly loading Pt NPs (5–8 nm) onto the support of ultrasmall EMT zeolite (15–20 nm), a kind of low-silica microporous aluminosilicate material.
3434	203	Ultrasensitive photoelectrochemical detection of microRNA on paper by combining a cascade nanozyme-engineered biocatalytic precipitation reaction and target-triggerable DNA motor	https://doi.org/10.1021/acssensors.0c00632	Composite	Au nanoparticles (NPs) modified by cyclodextrin (Au@CD)
3435	204	Nanozymes-based biosensors for food quality and safety	https://doi.org/10.1016/j.trac.2020.115841		Review
3436	205	Rosette-shaped graphitic carbon nitride acts as a peroxidase mimic in a wide pH range for fluorescence-based determination of glucose with glucose oxidase.	https://doi.org/10.1007/s00604-020-04249-z	Carbon	Rosette-shaped graphitic carbon nitride (rosette-GCN)
3437	206	Introducing a nanozyme-based sensor for selective and sensitive detection of mercury(II) using its inhibiting effect on production of an indamine polymer through a stable n-electron irreversible system	https://doi.org/10.1007/s11696-019-00981-w	Metal	Au-nanozyme
3438	207	Insights into Cronobacter sakazakii biofilm formation and control strategies in the food industry	https://doi.org/10.1016/j.eng.2020.02.007		Review
3439	208	Blue Light-Gated Reversible Silver Nanozyme Reaction Networks that Achieve Life-like Adaptivity	https://doi.org/10.1021/acssuschemeng.9b07009	Metal	silver nanoparticles (AgNPs)
3440	209	Protein-Supported RuO2 Nanoparticles with Improved Catalytic Activity, In Vitro Salt Resistance, and Biocompatibility: Colorimetric and Electrochemical Biosensing of Cellular H2O2	https://doi.org/10.1021/acsami.0c00778	Metal oxide	RuO2NP synthesis (BSA-RuO2NPs) supported by bovine serum albumin (BSA).
3441	210	Gold nanoparticles doped metal-organic frameworks as near-infrared light-enhanced cascade nanozyme against hypoxic tumors	https://doi.org/10.1007/s12274-020-2668-1	Composite	gold nanoparticles (AuNPs) doped iron-based metal-organic frameworks (GIM)
3442	211	A Cu2O-CDs-Cu three component catalyst for boosting oxidase-like activity with hot electrons	https://doi.org/10.1016/j.cej.2019.122484	Composite	Cu2O-CDs (carbon dots)-Cu three component oxidase-like catalyst
3443	212	MoOx quantum dots with peroxidase-like activity on microfluidic paper-based analytical device for rapid colorimetric detection of H2O2 released from PC12 cells	https://doi.org/10.1016/j.snb.2019.127512	Metal oxide	water-soluble molybdenum oxide quantum dots (MoOx QDs)
3444	213	A novel signal amplification strategy based on the competitive reaction between 2D Cu-TCPP(Fe) and polyethyleneimine (PEI) in the application of an enzyme-free and ultrasensitive electrochemical immunosensor for sulfonamide detection	https://doi.org/10.1016/j.bios.2019.111883	MOF	2D Cu-TCPP(Fe)
3445	214	3, 4: 9, 10-perylene tetracarboxylic acid-modified zinc ferrite with the enhanced peroxidase activity for sensing of ascorbic acid	https://doi.org/10.1016/j.colsurfa.2019.124250	Metal oxide	3,4:9,10-perylene tetracarboxylic acid (PTCA) modified litchi-like zinc ferrite (ZnFe2O4)
3446	215	Hydrogel-based artificial enzyme for combating bacteria and accelerating wound healing	https://doi.org/10.1007/s12274-020-2636-9	Others	the hydrogel-based artificial enzyme composed of copper and amino acids possessed intrinsic peroxidase-like catalytic activity
3447	216	Graphene oxide as a photocatalytic nuclease mimicking nanozyme for DNA cleavage	https://doi.org/10.1007/s12274-020-2629-8	Carbon	GO
3448	217	Colorimetric determination of ascorbic acid using a polyallylamine-stabilized IrO 2/graphene oxide nanozyme as a peroxidase mimic	https://doi.org/10.1007/s00604-019-3897-4	Composite	polyallylamine(PAH)-stabilized IrO2/graphene oxide(GO) nanozyme
3449	218	Carbon dot-based composites for catalytic applications	https://doi.org/10.1039/D0GC01014F		review
3450	219	Antioxidant Nanotherapies for the Treatment of Inflammatory Diseases	https://doi.org/10.3389/fbioe.2020.00200		review
3451	220	Glucose-responsive cascaded nanocatalytic reactor with self-modulation of the tumor microenvironment for enhanced chemo-catalytic therapy	https://doi.org/10.1039/D0MH00105H	Composite	MoS2@CGTC nanocatalytic reactor(NCR)
3452	221	Vitamin B2 functionalized iron oxide nanozymes for mouth ulcer healing	https://doi.org/10.1007/s11427-019-9590-6	Composite	Vitamin B2(VB2) functionalized iron oxide nanozymes(IONzymes)
3453	222	A Heparinase Sensor Based on a Ternary System of Hg2+–Heparin–Osmium Nanoparticles	https://doi.org/10.1021/acs.analchem.9b05222	Composite	Hg2+–heparin–osmium nanoparticles (OsNPs)
3454	223	Laccase immobilized peroxidase mimicking magnetic metal organic frameworks for industrial dye degradation	https://doi.org/10.1016/j.biortech.2020.124035	Composite	Laccase immobilized peroxidase mimicking magnetic metal organic frameworks(laccase@MMOFs)
3455	224	High-performance dual-channel ratiometric colorimetric sensing of phosphate ion based on target-induced differential oxidase-like activity changes of Ce-Zr bimetal-organic …	https://doi.org/10.1016/j.snb.2020.128546	MOF	oxidized UiO-66(Ce/Zr)
3456	225	Nanomaterial-mediated paper-based biosensors for colorimetric pathogen detection	https://doi.org/10.1016/j.trac.2020.116038		review
3457	226	Platinum Nanozyme-Triggered Pressure-Based Immunoassay Using a Three-Dimensional Polypyrrole Foam-Based Flexible Pressure Sensor	https://doi.org/10.1021/acsami.0c12074	Metal	platinum nanoparticles(Pt NPs)
3458	227	Single Iron Site Nanozyme for Ultrasensitive Glucose Detection	https://doi.org/10.1002/smll.202002343	unsure	single iron site nanozyme (Fe SSN)
3459	228	Nanozyme-based sensing platforms for detection of toxic mercury ions: An alternative approach to conventional methods	https://doi.org/10.1016/j.talanta.2020.120939		review
3460	229	Tailoring a robust nanozyme formulation based on surfactant stabilized lipase immobilized onto newly fabricated magnetic silica anchored graphene nanocomposite: Aggrandized stability and application	https://doi.org/10.1016/j.msec.2020.110883	Composite	lipase immobilized on Fe3O4/SiO2/Gr NC
3461	230	Hollow magnetic nanosystem-boosting synergistic effect between magnetic hyperthermia and sonodynamic therapy via modulating reactive oxygen species and heat shock proteins	https://doi.org/10.1016/j.cej.2020.124521	Composite	HP-HIONs@PDA-PEG containing hollow magnetic nanoparticles (HIONs), hematoporphyrin (HP), polydopamine (PDA), and polyethylene glycol (PEG)
3462	231	Endogenous Hydrogen Sulfide-Triggered MOF-Based Nanoenzyme for Synergic Cancer Therapy	https://doi.org/10.1021/acsami.0c08659	MOF	H2S-activated copper metal–organic framework (Cu-MOF; HKUST-1) nanoenzyme
3463	232	Gold alloy-based nanozyme sensor arrays for biothiol detection	https://doi.org/10.1039/D0AN00451K	Multi-metal	AuPtRu alloy
3464	233	Catalytically Active Peptide–Gold Nanoparticle Conjugates: Prospecting for Artificial Enzymes	https://doi.org/10.1002/anie.201908625		review
3465	234	Cadmium cobaltite nanosheets synthesized in basic deep eutectic solvents with oxidase-like, peroxidase-like, and catalase-like activities and application in the colorimetric assay of glucose	https://doi.org/10.1007/s00604-020-04298-4	Multi-metal	Cadmium cobaltite (CdCo2O4) nanosheets
3466	235	Coupling Two Sequential Biocatalysts with Close Proximity into Metal–Organic Frameworks for Enhanced Cascade Catalysis	https://doi.org/10.1021/acsami.0c04317	Composite	GOx&PVI-hemin@ZIF-8 composite
3467	257	Ti3C2Tx MXene-derived TiO2/C-QDs as oxidase mimics for the efficient diagnosis of glutathione in human serum	https://doi.org/10.1039/c9tb02478f	Composite	quantum dots of TiO2 loaded on carbon (TiO2/C-QDs)
3468	258	Biomineralization-inspired nanozyme for single-wavelength laser activated photothermal-photodynamic synergistic treatment against hypoxic tumors	https://doi.org/10.1039/c9nr08930f	Composite	RuO2@BSA@IR-808-Br2 (RBIR)
3469	259	Intracellular Antioxidant Activity of Biocompatible Citrate-Capped Palladium Nanozymes	https://doi.org/10.3390/nano10010099	Metal	citrate-capped PdNPs
3470	260	Molecule-gated surface chemistry of Pt nanoparticles for constructing activity-controllable nanozymes and a three-in-one sensor	https://doi.org/10.1039/c9an01956a	Metal	citrate-capped Pt nanoparticles (PtNPs)
3471	261	Nanozyme chemiluminescence paper test for rapid and sensitive detection of SARS-CoV-2 antigen	https://doi.org/10.1016/j.bios.2020.112817	Composite	Co–Fe nanoparticles@hemin
3472	264	A new nanozyme with peroxidase-like activity for simultaneous phosphoprotein isolation and detection based on metal oxide affinity	https://doi.org/10.1016/j.cej.2020.126357	Metal oxide	Monodisperse-porous cerium oxide microspheres
3473	266	Boron-doped Fe-N-C single-atom nanozymes specifically boost peroxidase-like activity	https://doi.org/10.1016/j.nantod.2020.100971	Single-atom	Boron-dopedFe-N-Csingle-atom
3474	267	Dual detoxification and inflammatory regulation by ceria nanozymes for drug-induced liver injury therapy	https://doi.org/10.1016/j.nantod.2020.100925	Metal oxide	ceria nanozymes(CeNZs)
3475	268	Gold nanoparticles mediated designing of versatile aptasensor for colorimetric/electrochemical dual-channel detection of aflatoxin B1	https://doi.org/10.1016/j.bios.2020.112443	Composite	Fe3O4@Au
3476	269	Cu2MoS4 Nanozyme with NIR‐II Light Enhanced Catalytic Activity for Efficient Eradication of Multidrug‐Resistant Bacteria	https://doi.org/10.1002/smll.202001099	Sulfide	Cu2MoS4 nanoplates
3477	270	Smartphone-assisted off-on photometric determination of phosphate ion based on target-promoted peroxidase-mimetic activity of porous CexZr1-xO2 (x >= 0.5) nanocomposites	https://doi.org/10.1016/j.envres.2020.109921	Metal oxide	CexZr1-xO2
3478	271	Facile synthesis of magnetic hierarchical flower-like Co3O4 spheres: Mechanism, excellent tetra-enzyme mimics and their colorimetric biosensing	https://doi.org/10.1016/j.bios.2020.112342	Metal oxide	Magnetic hierarchical flower-like Co3O4 spheres
3479	272	Persistent Regulation of Tumor Hypoxia Microenvironment via a Bioinspired Pt‐Based Oxygen Nanogenerator for Multimodal Imaging‐Guided Synergistic Phototherapy	https://doi.org/10.1002/advs.201903341	Composite	ICG-Pt-decorated MOF@octahedral gold nanoshells@human serum albumin-chelated gadolinium (PtMGs)
3480	273	Porous Pt Nanospheres Incorporated with GOx to Enable Synergistic Oxygen‐Inductive Starvation/Electrodynamic Tumor Therapy	https://doi.org/10.1002/advs.202001223	Metal	porous platinum nanospheres (pPts) incorporated with GOx molecules (PtGs)
3481	274	Electrochemical and sensing properties of Prussian Blue based nanozymes “artificial peroxidase”	https://doi.org/10.1016/j.jelechem.2020.114048	Others	Prussian Blue
3482	275	Biomimetic graphene oxide-cationic multi-shaped gold nanoparticle-hemin hybrid nanozyme: Tuning enhanced catalytic activity for the rapid	https://doi.org/10.1016/j.talanta.2020.120990	Composite	graphene oxide(GO)-cationic multi-shaped gold nanoparticle(AuNP)-hemin hybrid nanozyme
3483	276	Embedding Functional Biomacromolecules within Peptide‐Directed Metal–Organic Framework (MOF) Nanoarchitectures Enables Activity Enhancement	https://doi.org/10.1002/anie.202005529	Composite	2D mesoporous spindle-shaped MOFs architectures (2D MSMOFs)
3484	277	Hollow Magnetic Nanocatalysts Drive Starvation–Chemodynamic–Hyperthermia Synergistic Therapy for Tumor	https://doi.org/10.1021/acsnano.0c00910	Composite	glucose oxidase (GOD)-loaded hollow iron oxide nanocatalysts (HIONCs)
3485	278	Enhanced catalytic activity under non-equilibrium conditions	https://doi.org/10.1038/s41565-020-0734-1	Metal	hydrogel containing gold nanoparticles
3486	280	Design and application of proximity hybridization-based multiple stimuli-responsive immunosensing platform for ovarian cancer biomarker detection	https://doi.org/10.1016/j.bios.2020.112201	Sulfide	MoS2 nanosheets (MoS2 NSs)
3487	281	Construction of Self-activated Cascade Metal− Organic Framework/Enzyme Hybrid Nanoreactors as Antibacterial Agents	https://doi.org/10.1016/j.colsurfb.2020.111001	Composite	MIL@GOx-MIL nanoreactors (NRs)
3488	282	Single-atom iron containing nanozyme with peroxidase-like activity and copper nanoclusters based ratio fluorescent strategy for acetylcholinesterase activity sensing	https://doi.org/10.1016/j.snb.2020.128023	Single-atom	single-atom iron anchored on N-doped porous carbon (Fe-SAs/NC)
3489	283	Ir nanoparticles with multi-enzyme activities and its application in the selective oxidation of aromatic alcohols	https://doi.org/10.1016/j.apcatb.2020.118725	Metal	citrate capped iridium nanoparticles (Cit-IrNPs)
3490	284	Adaptive Chemoenzymatic Microreactors Composed of Inorganic Nanoparticles and Bioinspired Intrinsically Disordered Proteins	https://doi.org/10.1002/anie.202000835	Other	low complexity domains (LCDs)
3491	285	Peroxidase‐Like Nanozymes Induce a Novel Form of Cell Death and Inhibit Tumor Growth In Vivo	https://doi.org/10.1002/adfm.202000647	Metal oxide	Fe3O4
3492	287	2D/2D h‐BN/N‐doped MoS2 Heterostructure Catalyst with Enhanced Peroxidase‐like Performance for Visual Colorimetric Determination of H2O2	https://doi.org/10.1002/asia.201901753	Composite	hexagonal boron nitride (h-BN) and nitride doped molybdenum disulfide (N-MoS2) nano-composites (h-BN/N-MoS2)
3493	288	Chemically modified carbon nitride-chitin-acetic acid hybrid as a metal-free bifunctional nanozyme cascade of glucose oxidase-peroxidase for “click off” colorimetric detection of peroxide and glucose	https://doi.org/10.1016/j.bios.2020.112072	Composite	modified graphitic carbon nitride (MGCN) and chitin and acetic acid (AcOH) hybrid (MGCN-chitin-AcOH)
3494	289	A facile colorimetric sensor for ultrasensitive and selective detection of Lead(II) in environmental and biological samples based on intrinsic peroxidase-mimic activity of WS2 nanosheets	https://doi.org/10.1016/j.aca.2020.01.043	Sulfide	WS2 nanosheets
3495	291	Controlled formation of porous CuCo2O4 nanorods with enhanced oxidase and catalase catalytic activities using bimetal-organic frameworks as templates	https://doi.org/10.1016/j.colsurfb.2019.110764	Metal oxide	CuCo2O4 nanorods
3496	292	Nonrecurring Circuit Nanozymatic Enhancement of Hypoxic Pancreatic Cancer Phototherapy Using Speckled Ru–Te Hollow Nanorods	https://doi.org/10.1021/acsnano.9b09974	Metal	speckled RuTe hollow nanorods (RuTeNRs)
3497	293	The Fe–N–C oxidase-like nanozyme used for catalytic oxidation of NOM in surface water	https://doi.org/10.1016/j.watres.2020.115491	Other	Fe-N-C oxidase-like nanozyme (FeNZ)
3498	294	Discrete Hf18 metal‐oxo cluster as a heterogeneous nanozyme for site‐specific proteolysis	https://doi.org/10.1002/anie.202001036	metal-oxo cluster	hafnium (IV) polynuclear cluster, Hf 18
3499	295	Selection and characterization of DNA aptamers for constructing colorimetric biosensor for detection of PBP2a	https://doi.org/10.1016/j.saa.2019.117735	Composite	graphene oxidase (GO)/Au (GO/Au)
3500	296	Persistent peroxidase mimics of graphene oxide anchored cerium molybdate sensor: An effective colorimetric detection of S2− and Sn2+ ions	https://doi.org/10.1016/j.microc.2019.104290	Others	cerium molybdate (CeM) and GO-cerium molybdate (GOCeM)
3501	298	Sensitive chemical sensor array based on nanozymes for discrimination of metal ions and teas	https://doi.org/10.1002/bio.3730	Composite	The indicators for the sensor array are three kinds of nanozymes mimicking laccase (Cu‐ATP, Cu‐ADP, Cu‐AMP)
3502	300	Macrophage polarization by plasma sprayed ceria coatings on titanium-based implants: Cerium valence state matters	https://doi.org/10.1016/j.apsusc.2019.144070	Composite	the ceria A-III (low Ce4+/Ce3+ ratio) and B-IV (high Ce4+/Ce3+ ratio) coatings applied to the titanium substrates
3503	301	Mimicking peroxidase active site microenvironment by functionalized graphene quantum dots	https://doi.org/10.1007/s12274-020-2678-z	Composite	we herein report a novel histidine-functionalized graphene quantum dot (His-GQD)/hemin complex
3504	302	Molybdenum disulfides nanoflowers anchoring iron-based metal organic framework: A synergetic catalyst with superior peroxidase-mimicking activity for biosensing	https://doi.org/10.1016/j.snb.2019.127530	Composite	A novel nanostructure MoS2 nanoflowers anchoring iron(III)-based metal-organic framework MIL-101(Fe) [Fe3O(H2O)2Cl(O2C–C6H4−CO2)3], named MoS2-MIL-101(Fe), was prepared by growing MIL-101(Fe) crystals with as
3505	303	Quercetin@ ZIF-90 as a novel antioxidant for label-free colorimetric ATP sensing at neutral pH	https://doi.org/10.1016/j.snb.2019.127324	Composite	we report a facile approach to fabricate Quercetin@ZIF-90 (QZ) nm
3506	304	Oligonucleotide-induced regulation of the oxidase-mimicking activity of octahedral Mn 3 O 4 nanoparticles for colorimetric detection of heavy metals	https://doi.org/10.1007/s00604-019-4069-2	Metal oxide	A colorimetric assay for the determination of heavy metal ions is presented that is based on the regulation of the oxidase-mimicking activity of Mn3O4 nanoparticles (NPs)
3507	305	Oxidase-Inspired Selective 2e/4e Reduction of Oxygen on Electron-Deficient Cu	https://doi.org/10.1021/acsami.9b20920	Composite	Mn3O4 nanoparticles (Mn3O4 NPs)
3508	309	Graphdiyne oxide: a new carbon nanozyme	https://doi.org/10.1039/D0CC01840F	Carbon